Tau Mutations as a Novel Risk Factor for Cancer—Letter

Angela B. Deutschländer,Bradley F. Boeve,Howard J. Rosen,Adam L. Boxer,Zbigniew K. Wszolek

CANCER RESEARCH（2018）

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摘要

Rossi and colleagues (2018) recently reported an increased cancer frequency in 15 families with frontotemporal lobar degeneration (FTLD) and mutations in the microtubule-associated protein tau ( MAPT ) gene (15% of 162 subjects of MAPT FTLD kindreds; 9% of 717 controls; ref. [1][1]). They concluded

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