Copper Mediated Three‐Component Reactions of Alkynes, Azides, and Propargylic Carbonates: Synthesis of 5‐Allenyl‐1,2,3‐Triazoles

Advanced Synthesis and Catalysis(2018)

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摘要
A copper‐mediated one‐pot sequential reaction of terminal alkynes, azides, and propargylic carbonates is reported. The three component reaction occurs readily at room temperature to afford a 5‐allenyl‐1,2,3‐triazoles in high yields, providing a straightforward approach to 1,3,5‐trisubstituted triazoles using easily available Cu(I) reagent.
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关键词
alkyne,azide,propargylic carbonates,triazole,allenyl,copper
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