Pterostilbene inhibited advanced glycation end products (AGEs)-induced oxidative stress and inflammation by regulation of RAGE/MAPK/NF-κB in RAW264.7 cells
Journal of Functional Foods(2018)
摘要
•Pterostilbene inhibited AGEs-induced oxidative stress.•Pterostilbene reduced AGEs-induced gene expression of inflammatory mediators.•Pterostilbene acted via RAGE/MAPK/NF-κB pathway.•Pterostilbene increased CD36 expression to remove local AGEs.
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关键词
Pterostilbene,Methylglyoxal,Inflammation,Oxidation,RAGE,Macrophage
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