Metas de colesterol LDL en pacientes sometidos a revascularización periférica

Revista Argentina de Cardiología(2017)

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摘要
espanolIntroduccion. Los pacientes con enfermedad vascular periferica representan un grupo de alto riesgo de eventos cardiovasculares por lo que deben alcanzar metas de prevencion secundaria de enfermedad cardiovascular. Objetivos. Determinar que porcentaje de pacientes sin antecedentes de enfermedad coronaria sometidos a cirugia vascular (CV) alcanzan las metas de colesterol luego de ser intervenidos en relacion a pacientes sometidos a cirugia de revascularizacion miocardica (CRM) electiva. Materiales y Metodos Se comparo el grado de control de dislipemia de una cohorte retrospectiva de pacientes sometidos a CV sin antecedentes clinicos de enfermedad coronaria en relacion a pacientes sometidos a cirugia de revascularizacion coronaria. Resultados. Se siguieron 468 individuos, 98 operados de CV y 370 de CRM por un periodo de 18 meses. La media de LDL a los 6 meses de la cirugia fue significativamente menor en los coronarios que en los vasculares (84.7±25 vs. 98.8±35 mg/dl; p=0.001). Esta diferencia se mantuvo a los 12 meses post operatorio (91,6±28.5 vs. 102 ±39; p=0.04) pero se pierde a los 18 meses (88±26 vs 93.3±23 mg/dl; p=0.25) La tasa de alcance de metas de LDL EnglishBackground: Patients with peripheral vascular disease represent a group at high risk of cardiovascular events, and must therefore achieve the secondary prevention goals recommended in the guidelines. Objectives: Primary: To determine what percentage of patients undergoing peripheral revascularization surgery reached LDL cholesterol goals at 6 months of the intervention compared with patients undergoing coronary artery bypass grafting. Secondary: To determine the percentage of patients reaching these levels at 18 months of follow-up, the percentage of patients with total cholesterol dosage and lipid fraction (LDL-C, HDL-C and TG) assessment at 6 and 18 months of follow-up and the percentage of statin use during the previous year and during the long term follow-up after surgery. Methods: The degree of lipid control in a retrospective cohort of patients undergoing peripheral revascularization surgery was compared with another group of patients undergoing coronary artery bypass grafting at 6 months and 18 months of the procedure. Results: A total of 468 individuals, 98 undergoing surgery for peripheral vascular disease and 370 for coronary artery disease were followed up for a period of 18 months. Mean LDL-C at 6 months of surgery was significantly higher in the vascular than in the coronary patients (98.8±35 mg/dl vs. 84.7±25 mg/dl, p=0.001), but lost significance at 18 months (93.3±23 mg/dl vs. 88±26 mg/ dl, p=0.25). The percentage of patients achieving LDL-C targets
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colesterol ldl
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