Synthesis, reactivities and anti-cancer properties of ruthenium(II) complexes with a thiaether macrocyclic ligand ☆

Hannah A. O’Riley,Aviva Levina,Jade B. Aitken,Peter A. Lay

Inorganica Chimica Acta（2017）

引用 7|浏览16

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摘要

The anti-cancer drugs, [RuX2([9]aneS3)(S-dmso)] (X=Cl, Br), are not cytotoxic but they have strong anti-invasive activities for highly invasive MDA-MB-231 breast cancer cells. This indicates their potential to be used as anti-metastatic drugs.

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关键词

Ruthenium(II),Thiaether,Halido,Substitution reactions,Anti-cancer properties,Invasion assays

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