Histone deacetylase 3 (HDAC 3) as emerging drug target in NF-κB-mediated inflammation.

Niek G. J. Leus,Martijn R. H. Zwinderman,Frank J. Dekker

Current Opinion in Chemical Biology（2016）

引用 102|浏览2

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摘要

•HDAC 3 plays a key role in NF-κB-mediated signaling.•HDAC inhibitors demonstrate promising anti-inflammatory effects.•Selective HDAC 3 inhibitors have potential for treatment of inflammatory diseases.

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