The α-thio and/or β-γ-hypophosphate analogs of ATP as cofactors of T4 DNA ligase.

Roza Pawlowska,Dariusz Korczynski,Barbara Nawrot,Wojciech J. Stec,Arkadiusz Chworos

Bioorganic Chemistry（2016）

引用 6|浏览21

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摘要

The T4 DNA ligase accepts ATPαS-SP and β,γ-hypo-ATP (oxo) for DNA end-joining reaction, but does not accept ATPαS-RP neither both epimers of β,γ-hypo-ATPαS as cofactors.

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关键词

T4 DNA ligase,Modified ATP,Hypophosphates,Phosphorothioates

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