An unusual case of intrathoracic Castleman’s Disease

Castlemanu0027s disease (CD) is a rare, non-clonal disease of the lymph nodes that may develop at a single site (unicentric form) or multiple sites (multicentric form) throughout the body. Histopathologically, CD is differentiated into a hyaline vascular variant, a plasma cell variant and a mixed cell type. Classically, unicentric CD is of the hyaline vascular variety while multicentric disease is of the plasma cell or mixed cellularity forms. We report an asymptomatic patient whose imaging revealed isolated left hilar lymphadenopathy. After thoracotomy, lymph node excision biopsy was performed, and histopathological examination revealed plasma cell histology. Unicentric plasma cell presentation is a rarely seen variant of CD.