Design and construction of a new human naïve single-chain fragment variable antibody library, IORISS1

Michela Pasello,Silvia Zamboni,Alessandra Mallano,Michela Flego,Piero Picci,Maurizio Cianfriglia,Katia Scotlandi

Journal of Biotechnology（2016）

引用 8|浏览231

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摘要

•Design and construction of a new human naïve antibody phage display library IORISS1.•Optimized method used to generate a new human naïve phage library.•Diversity of V genes obtained by careful amplification.

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关键词

Biopanning,IORISS1,Monoclonal antibody,Naïve library single-chain variable fragment,Phage display

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