DPD Scintigraphy for diagnosis of amyloidosis in 1191 patients– a single centre experience

David Hutt, Helen Mcphillips, Stephanie Mcknight,Julian Gillmore,Carol Whelan,Helen Lachmann,Ashutosh Wechalekar,Philip Hawkins

Orphanet Journal of Rare Diseases（2015）

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摘要

Background 99mTechnetium labelled 3,3-diphosphono-1,2-propanodicarboxylic acid (99mTc-DPD) scintigraphy has been repurposed in recent years as a sensitive non-invasive method for imaging transthyretin (ATTR) cardiac amyloid. We have routinely performed DPD scans since June 2010 at the National Amyloidosis Centre in London, and review here our findings in a large cohort of mostly British patients.

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关键词

Amyloidosis, Cardiac Amyloidosis, Cardiac Uptake, Familial Amyloid Polyneuropathy, Positive Scan

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