Vitamin B3 impairs reverse cholesterol transport in Apolipoprotein E-deficient mice.

Karen Alejandra Méndez-Lara,David Santos,Núria Farré,Madalina Nicoleta Nan,Víctor Pallarès,Antonio Pérez-Pérez,Núria Alonso,Joan Carles Escolà-Gil,Francisco Blanco-Vaca,Josep Julve

Clínica e Investigación en Arteriosclerosis (English Edition)（2019）

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摘要

The data from this study show that the administration of NAM to KOE mice impaired m-RCT in vivo. This finding was partly due to a defective hepatic clearance of plasma non-HDL.

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关键词

HDL function,Hypercholesterolemia,Atherosclerosis

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