Comparative effectiveness of multi-fraction stereotactic radiosurgery for surgically resected or intact large brain metastases from non-small-cell lung cancer (NSCLC)

Giuseppe Minniti,Claudia Scaringi,Gaetano Lanzetta,Dimitri Anzellini,Federico Bianciardi,Barbara Tolu,Roberta Morace,Andrea Romano,Mattia Osti,PierCarlo Gentile,Sergio Paolini

Lung Cancer（2019）

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摘要

•Postoperative SRS is usually recommended for resected brain metastases.•3 x 9 Gy demonstrates activity in both intact and resected large NSCLC metastases.•Local control is comparable between resected and intact large brain metastases.•A worse safety profile can be expected after surgery and postoperative SRS (3 x 9 Gy).

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关键词

Stereotactic radiosurgery,Resection cavity,NSCLC brain metastases,Multi-Fraction stereotactic radiosurgery,EGFR

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