Radiation-induced and neurofibromatosis-associated malignant peripheral nerve sheath tumors (MPNST) have worse outcomes than sporadic MPNST.

Ruoyu Miao,Haotong Wang,Alex Jacobson,Anna P Lietz,Edwin Choy,Kevin A Raskin,Joseph H Schwab,Vikram Deshpande,G Petur Nielsen,Thomas F DeLaney,Gregory M Cote,Francis J Hornicek,Yen-Lin E Chen

Radiotherapy and Oncology（2019）

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摘要

•Both radiation-induced and neurofibromatosis-associated MPNSTs have poorer prognosis than sporadic MPNSTs.•Complete resection of the tumor is a significant prognostic factor for MPNST.•Surgery with adjuvant radiotherapy is related to improved local control in patients with positive surgical margins.

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关键词

Malignant peripheral nerve sheath tumor,Survival,Local control,Radiation,Neurofibromatosis

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