High GD2 expression defines breast cancer cells with enhanced invasiveness.

Maryam Mansoori,Raheleh Roudi,Ata Abbasi,Maryam Abolhasani,Isa Abdi Rad,A Shariftabrizi,Zahra Madjd

Experimental and Molecular Pathology（2019）

引用 27|浏览7

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摘要

•Increased expression of GD2 confers aggressive tumor behavior in breast cancer.•Positive correlation found between CD44/CD24 population with higher differentiation.•GD2 may be considered as an effective diagnostic and monitoring target in clinic.•GD2+/CD44+/CD24− detected in larger size and lymph node involvement breast cancer.

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关键词

Breast cancer,Cancer stem cells,GD2,Tissue microarray,CD44,CD24

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