A prospective phase II trial on reirradiation of brain metastases with radiosurgery.

Ernesto Maranzano,Sara Terenzi,Paola Anselmo,Michelina Casale,Fabio Arcidiacono,Fabio Loreti,Alessandro Di Marzo,Lorena Draghini,Marco Italiani,Fabio Trippa

Clinical and Translational Radiation Oncology（2019）

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摘要

•Reirradiation with radiosurgery of brain metastases is feasible and safe.•Good KPS and controlled systemic disease are most important selection criteria.•An accurate patient selection is essential to avoid brain toxicity.•If diameter is ≤ 2 cm and dose ≤ 20 Gy local control is high without late toxicity.

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关键词

Recurrent brain metastases,Reirradiation,Radiosurgery,Whole brain radiotherapy,Brain radionecrosis

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