Toll-Like Receptor 4 Regulates Subventricular Zone Proliferation and Neuroblast Migration after Experimental Stroke.

Sara Palma-Tortosa,Olivia Hurtado,Jesús Miguel Pradillo, Raquel Ferreras-Martín,Isaac García-Yébenes,Alicia García-Culebras,Ana Moraga,María Ángeles Moro,Ignacio Lizasoain

Brain, Behavior, and Immunity（2019）

引用 25|浏览15

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摘要

•TLR4 is involved in the conversion of NSC to neuroblast.•TLR4 promotes the migration of neuroblasts after experimental stroke.•HMGB1 is elevated in cerebrospinal fluid 1 day after stroke.•HMGB1 is implicated in SVZ cells proliferation and NSC differentiation.

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关键词

FDA,TLR4,SVZ,HMGB1,RMS,NSPCs,NSC,NPC,LPS,DG,CSF,BDNF,SDF-1α,LPSRS,TLR2,RAGE

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