Chronic adult-onset of growth hormone/IGF-I hypersecretion improves cognitive functions and LTP and promotes neuronal differentiation in adult rats.

Juan Francisco Martín-Rodríguez,Víctor Darío Ramos-Herrero,Gloria G Parras,Álvaro Flores-Martínez,Ainara Madrazo-Atutxa,David A Cano,Agnès Gruart,José María Delgado-García,Alfonso Leal-Cerro,Rocío Leal-Campanario

Acta physiologica (Oxford, England)（2020）

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摘要

Thus, adult-onset hypersecretion of GH/IGF-I improves neurocognitive functions, long-term memories, experimental LTP, and neural differentiation, migration, and maturation. This article is protected by copyright. All rights reserved.

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关键词

LTP ,growth hormone,growth-hormone-secreting tumors,insulin-like growth factor type I,neurogenesis,operant conditioning,passive avoidance,rats

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