Activation of the prostaglandin E EP2 receptor attenuates renal fibrosis in unilateral ureteral obstructed mice and human kidney slices.

In conclusion, this study demonstrates that stimulation of the EP receptor effectively mitigates renal fibrogenesis in various fibrosis models. These findings warrant further research into the clinical application of butaprost, or other EP agonists, for the inhibition of renal fibrosis. This article is protected by copyright. All rights reserved.