Universally non-immunogenic iPSCs

NATURE BIOMEDICAL ENGINEERING（2019）

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摘要

Inactivation of the major histocompatibility complex and overexpression of the transmembrane protein CD47 renders induced pluripotent stem cells invisible to the immune system of the host.

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关键词

Cell transplantation,Induced pluripotent stem cells,Transplant immunology,Transplantation tolerance,Biomedicine,general,Biomedical Engineering/Biotechnology

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