Non-invasive diagnosis of early-stage lung cancer using high-throughput targeted DNA methylation sequencing of circulating tumor DNA (ctDNA)
Theranostics, Volume 9, Issue 7, 2019, Pages 2056-2070.
Early-stage lung cancercirculating tumor DNAhigh-throughput targeted DNA methylation sequencing
LDCT screening can identify early-stage lung cancers yet introduces excessive false positives and it remains a great challenge to differentiate malignant tumors from benign solitary pulmonary nodules, which calls for better non-invasive diagnostic tools. We performed DNA methylation profiling by high throughput DNA bisulfite sequencing ...More
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