Patients with Alzheimer's disease who carry the APOE ε4 allele benefit more from physical exercise.

Camilla Steen Jensen,Anja Hviid Simonsen,Volkert Siersma,Nina Beyer,Kristian Steen Frederiksen,Hanne Gottrup, Kristine Hoffman,Peter Høgh,Ruth Frikke-Schmidt,Nanna Aue Sobol,Gunhild Waldemar,Lene Wermuth,Steen Gregers Hasselbalch

Alzheimer's & Dementia: Translational Research & Clinical Interventions（2019）

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摘要

This exploratory study establishes a possible connection between the beneficial effects of exercise in AD and the patients' genotype. These findings, if validated, could greatly impact the clinical management of patients with AD and those at risk for developing AD.

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关键词

Alzheimer's disease,Exercise,APOE,Genetic,Intervention

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