IL-17-high asthma with features of a psoriasis immunophenotype.
Journal of Allergy and Clinical Immunology(2019)
摘要
The interleukin-17-high asthma phenotype, characterized by bronchial epithelial dysfunction, upregulated anti-microbial and inflammatory response, resembles the immunophenotype of psoriasis, including activation of the thromboxane B2 pathway which should be considered as a biomarker for this phenotype in further studies, including clinical trials targeting interleukin-17.
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关键词
IL-17,asthma,bronchial biopsies,bronchial brushings,biomarkers,psoriasis
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