The Effect of Hormonal Contraception on Cervico-Vaginal Mucosal Endpoints associated with Human Immunodeficiency Virus Acquisition.

Andrea Thurman,Neelima Chandra,Jill L Schwartz,Vivian Brache,Beatrice A Chen,Susana Asin,Christiane Rollenhagen,Betsy C Herold,Raina N Fichorova,Sharon L Hillier,Debra H Weiner,Christine Mauck,Gustavo F Doncel

AIDS research and human retroviruses（2019）

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摘要

Exposure to exogenous contraceptive hormones significantly increased vaginal immune cells and reduced CV pro-inflammatory cytokines and anti-microbial peptides. DMPA users showed higher susceptibility to HIV-1 ex vivo infection.

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