Effects of early life adversity and FKBP5 genotype on hippocampal subfields volume in major depression.

Pavol Mikolas,Leonardo Tozzi,Kelly Doolin,Chloe Farrell,Veronica O'Keane,Thomas Frodl

Journal of Affective Disorders（2019）

引用 33|浏览7

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摘要

•MDD patients had smaller volumes within the cornu ammonis and dentate gyrus.•MDD exposed to early life adversity had larger hippocampi and their subfields.•There was an interaction of FKBP5 and early life adversity in the HATA subfield.

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关键词

FKBP5,Early life adversity,Hippocampus,Hippocampal subfields,Major depression,rs1360780

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