Cerebellar inhibition in hepatic encephalopathy.

Shady Safwat Hassan,Thomas J Baumgarten,Anwar M Ali, Nur-Deniz Füllenbach,Markus S Jördens,Dieter Häussinger,Markus Butz,Alfons Schnitzler,Stefan Jun Groiss

Clinical Neurophysiology（2019）

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摘要

•Decreased cerebellar inhibition (CBI) suggests affection of the cerebellar efferent pathway in hepatic encephalopathy (HE).•The extent of CBI increases with disease severity.•The results suggest increase of the GABAergic tone in Purkinje cells with increasing severity of HE.

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关键词

Transcranial magnetic stimulation (TMS),Cerebellar inhibition (CBI),Hepatic encephalopathy (HE),Gamma Aminobutyric Acid (GABA),Critical flicker frequency (CFF),Score for assessment and rating of ataxia (SARA)

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