Lower cortisol levels and attenuated cortisol reactivity to daily-life stressors in adults with 22q11.2 deletion syndrome.

Esther D A van Duin,Thomas Vaessen,Zuzana Kasanova,Wolfgang Viechtbauer,Ulrich Reininghaus,Peter Saalbrink,Claudia Vingerhoets,Dennis Hernaus,Jan Booij,Ann Swillen,Jacob Vorstman,Thérèse van Amelsvoort,Inez Myin-Germeys

Psychoneuroendocrinology（2019）

引用 17|浏览19

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摘要

•Diurnal cortisol levels are significantly lower in adults with 22q11DS group compared to HCs.•22q11DS adults display significantly attenuated cortisol reactivity to activity-related stress compared to HCs•Cortisol levels and reactivity to stress in adults with 22q11DS are not related to psychiatric diagnosis or medication use.•Cortisol levels and reactivity to stress in adults with 22q11DS may indicate increased sensitization of the HPA-axis.

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关键词

Cortisol,Experience sampling method,22q11.2 deletion syndrome,Stress reactivity

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