Peptide Conjugates Of Lactoferricin Analogues And Antimicrobials - Design, Chemical Synthesis, And Evaluation Of Antimicrobial Activity And Mammalian Cytotoxicity.

Peptides(2019)

引用 16|浏览26
暂无评分
摘要
•8 new conjugates consisting of LFcinB analogues and three antimicrobials: CIP, LVX and FLC were synthesized.•Click reaction was used to synthesize FLC-based conjugates.•All studied peptide conjugates exhibited activity against Gram-positive bacteria.•The important role of disulfide bridge as a linker was revealed.•Synthesized conjugates showed relatively low cytotoxic effect.
更多
查看译文
关键词
Peptide conjugates,Antimicrobial peptides,Click chemistry,Disulfide bridge,Lactoferricin
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要