Quantitative RT-PCR-based miRNA profiling of blastemal Wilms' tumors from formalin-fixed paraffin-embedded samples.

Gergely Buglyó,Zsófia Magyar,Éva Romicsné Görbe,Rita Bánusz,Monika Csóka,Tamás Micsik, Zsanett Berki,Péter Varga,Zoltán Sápi,Bálint Nagy

Journal of Biotechnology（2019）

引用 7|浏览41

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摘要

•Extraction of miRNA is efficient from Wilms’ tumor FFPE samples.•Downregulation of miR-184 may be characteristic to a subset of blastemal tumors.•Loss of miR-203a may play a role in the pathogenesis of blastemal Wilms’ tumors.

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关键词

Wilms’ tumor,miR-184,miR-203a,miR-194-5p,miR-34c-5p,Quantitative real-time PCR

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