The GIRAFE phase II trial on MVCT-based "volumes of the day" and "dose of the day" addresses when and how to implement adaptive radiotherapy for locally advanced head and neck cancer.

Vincent Esteyrie,Baptiste Gleyzolle,Amélie Lusque,Pierre Graff,Anouchka Modesto,Michel Rives,Michel Lapeyre, Jacques Desrousseaux,Eliane Graulières, Gregory Hangard, François-Xavier Arnaud,Regis Ferrand,Jean-Pierre Delord,Muriel Poublanc,Muriel Mounier,Thomas Filleron,Anne Laprie

Clinical and Translational Radiation Oncology（2019）

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摘要

•The GIRAFE trial will evaluate an adaptive radiotherapy method.•48 patients will be included.•They will undergo 4 intermediate re-planning CTs ( iCTs) and 35 daily MVCT.•MVCT adaptive segmentation will be compared with manual recontouring.•Deformable contour deformation on iCTs will be compared with manual recontouring.

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ART,CT,CTV,DIR,DSC,GTV,H&N,iCT,ICRU,IMRT,IGRT,IUCT,MVCT,OAR,PET,PTV

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