Somatic and psychosocial determinants of symptom severity and quality of life in male and female patients with chronic pelvic pain syndrome.

•Somatic aspects measured by the intake of pain medication were associated with symptom severity only in the absence of psychosocial variables•The intake of pain medication, depressive symptoms and pain catastrophizing together significantly predicted higher CPPS symptom severity•Depression was consistently associated with symptom severity and physical and mental quality of life