Stratification of asthma phenotypes by airway proteomic signatures. James P R Schofield , Dominic Burg , Ben Nicholas , Fabio Strazzeri , Joost Brandsma , Doroteya Staykova , Caterina Folisi , Aruna T Bansal , Yang Xian , Yike Guo , Anthony Rowe , Julie Corfield , Susan Wilson , Jonathan Ward , Rene Lutter , Dominick E Shaw , Per S Bakke , Massimo Caruso , Sven-Erik Dahlen , Stephen J Fowler , Ildikó Horváth , Peter Howarth , Norbert Krug , Paolo Montuschi , Marek Sanak , Thomas Sandström , Kai Sun , Ioannis Pandis , John Riley , Charles Auffray , Bertrand De Meulder , Diane Lefaudeux , Ana R Sousa , Ian M Adcock , Kian Fan Chung , Peter J Sterk , Paul J Skipp , Ratko Djukanović Journal of Allergy and Clinical Immunology（2019）
摘要
This study provides further stratification of asthma currently classified by quantifying granulocytic inflammation and gives additional insight into their underlying mechanisms which could become targets for novel therapies.
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关键词
Asthma, proteomics, biomarkers, eosinophils, neutrophils
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