Human papillomavirus DNA detection, p16, and oral cavity cancer in a U.S. population.

Brenda Y Hernandez,Charles F Lynch, Owen T M Chan,Marc T Goodman,Elizabeth R Unger,Martin Steinau,Trevor D Thompson,Maura Gillison,Christopher Lyu,Mona Saraiya

Oral oncology（2019）

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摘要

Strong expression of p16 in a gingival tumor positive for HPV 18 is depicted. Of the 122 oral cavity cancer cases, joint positivity for HPV 16/18 and p16INK4a was observed in 33% (4/12) of gingival tumors compared to 0% (0/6)–8% (2/26) for other subsites (p = 0.01).

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关键词

HPV,Human papillomavirus,Oral cavity,Oral cancer,P16INK4a

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