Synthesis of TPEN variants to improve cancer cells selective killing capacity.
Bioorganic Chemistry(2019)
摘要
N,N,N′-tris(2-pyridylmethyl)-N′-ethyl-1,2-ethanenediamine (TPEEN) is a novel transition metal chelators derived from TPEN that generates reactive oxygen species (ROS) resulting in cell death.
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关键词
TPEN,Transition metals,ROS,Cancer,Cell death
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