Burn injury is associated with an infiltration of the wound site with myeloid-derived suppressor cells

Martin G. Schwacha,Shannon R. Scroggins,Robbie K. Montgomery,Susannah E. Nicholson,Andrew P. Cap

Cellular Immunology（2019）

引用 12|浏览6

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摘要

•MDSCs are found in the burn wound and uninjured skin, but not the skin of naïve mice.•TLR expression is suppressed on burn wound MDSCs.•Burn wound MDSCs constitutively produced both pro- and anti-inflammatory cytokines.•Burn wound M-MDSCs expressed both iNOS and ARG1.

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关键词

Toll-like receptors,Inflammation,Cytokines,iNOS,ARG1

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