A model-free technique based on computer vision and sEMG for classification in Parkinson's disease by using computer-assisted handwriting analysis.

•Computer-assisted handwriting analysis applied in Parkinson’s disease research.•Model-free technique for differentiating Parkinsonian patients from healthy subjects.•Finding most representative features and best writing patterns for Parkinson research.•Comparison of AI-based classification approaches for handwriting analysis.•Role of muscular activities on handwriting analysis applied to Parkinson research.