Synthesis and characterization of novel bromophenols: Determination of their anticholinergic, antidiabetic and antioxidant activities.

A series of novel bromophenol derivatives were synthesized and evaluated for their antioxidant activity, α-glycosidase and acetylcholinesterase enzymes inhibition properties. The most powerful inhibition was observed from (2,3-Dibromo-4-hydroxy-5-methoxyphenyl)(2,5-dibromo-4-methoxyphenyl)methanone as 4.31 ± 1.93 nM α-glycosidase enzyme, which promise as antidiabetic agent. This compound can be researched in further studies related diabetes mellitus as lead compound.