Expression of the growth hormone receptor isoforms and its correlation with the metabolic profile in morbidly obese subjects.

Endocrine(2019)

引用 4|浏览15
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摘要
The heterozygous GHR +3/-3 genotype is more prevalent in subjects with morbid obesity. Patients expressing the exon +3 and exon -3 isoforms in adipose tissue had a higher HbA1c, than those expressing only the exon -3 isoform.
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关键词
Adipose tissue,Exon 3 GHR,GH,GH Receptor,Metabolic syndrome,Morbid obesity
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