A Novel Next-Generation Sequencing Approach without Donor-Derived Material for Acute Rejection and Infection Monitoring in Solid Organ Transplantation

    Liuhong Zeng
    Liuhong Zeng
    Chunting Zheng
    Chunting Zheng
    Qing Yang
    Qing Yang
    Jibin Zhang
    Jibin Zhang
    Qiuhua Deng
    Qiuhua Deng
    Yongping Lin
    Yongping Lin
    Danxia Huang
    Danxia Huang
    Liping Liu
    Liping Liu

    Journal of Cancer Therapy, pp. 623-638, 2018.

    Cited by: 0|Bibtex|Views7|

    Abstract:

    Background: Donor-derived cell free DNA (ddcfDNA) has been reported as a universal noninvasive biomarker for rejection monitoringin heart, kidney, liver, and lung transplantation. Current approaches based on next-generationsequencing for quantification of ddcf DNA, although promising, may be restrictedby the requirement for donor material...More

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