A Novel Next-Generation Sequencing Approach without Donor-Derived Material for Acute Rejection and Infection Monitoring in Solid Organ Transplantation
Journal of Cancer Therapy, pp. 623-638, 2018.
Background: Donor-derived cell free DNA (ddcfDNA) has been reported as a universal noninvasive biomarker for rejection monitoringin heart, kidney, liver, and lung transplantation. Current approaches based on next-generationsequencing for quantification of ddcf DNA, although promising, may be restrictedby the requirement for donor material...More
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