Nanoscaled ultrasound contrast agents for enhanced sonothrombolysis.

J Brüßler,B Strehlow,A Becker,R Schubert,J Schümmelfeder,C Nimsky,U Bakowsky

Colloids and Surfaces B: Biointerfaces（2018）

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摘要

•Sonothrombolysis enhances recanalization of occluded blood vessels.•Thrombolytic effect of nanoscaled ultrasound contrast agent (NUSCA) was determined.•Weight reduction of more than 50% was found for low intensity 2.85 MHz ultrasound.•Fibrin network degradation of drugs was amplified by the NUSCA and ultrasound.

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关键词

Theranostic,Nanoscaled ultrasound contrast agent,Recanalization,Sonothrombolysis,Ultrasound

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