Gene score as predictor of hypertriglyceridemia in Czech population

Aim: Hypertriglyceridemia (HTG) is a common lipid disorder. It is supposed, that really high plasma levels of triglycerides (over 10 mmol/L) have strong genetic background. Rare mutations explain some cases, but in majority of the patients, the disease seems to be polygenic. Accumulation of risky alleles can nonlinearly increase the risk of HTG.