Growth hormone (GH) and triglyceride-rich lipoprotein (TRL) metabolism: Effect of one month of discontinued growth hormone treatment in growth hormone deficient patients

Aim: Growth hormone (GH) deficiency is associated with increased cardiovascular mortality. Insulin resistant states and lipid profile alterations with hypertriglyceridemia, decreased HDL cholesterol, increased small and dense LDL and postprandial hyperlipidemia are commonly observed in GH deficient patients but GH specific function in triglyceride-rich lipoprotein (TRL) metabolism regulation remains unclear.