Perturbation of metabolic pathways mediates the association of air pollutants with asthma and cardiovascular diseases.

Environment International(2018)

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摘要
•Strong association of long-term ultrafine particle exposure with adult-onset asthma•Linoleate metabolism and carnitine shuttle as “meeting-in-the-middle” pathways.•Metabolic pathways mediate the air pollution effects on health outcomes.
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关键词
Air pollution,Untargeted metabolomics,Metabolic pathways,Adult-onset asthma,Cardio-cerebrovascular diseases
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