Development of a domestic animal model for endometriosis: Surgical induction in the dog, pigs, and sheep

Emy E Varughese
Emy E Varughese
Carlos Ep Leonardi
Carlos Ep Leonardi

Journal of endometriosis and pelvic pain disorders, pp. 95-106, 2018.

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Abstract:

Background:Endometriosis affects one in ten women of reproductive age but it is diagnosed at advanced stages. Our objective was to develop a domestic animal model that would permit sequential assessment of endometriotic changes.Materials and methods:Surgical transplantation of endometrial tissue and fat (n = 4 grafts/tissue/animal) was do...More

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