Efficacy of Rituximab in Refractory Generalized anti-AChR Myasthenia Gravis.

Journal of neuromuscular diseases(2018)

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摘要
These results provide data on the effect of RTX in patients with severe, refractory anti-AChR Abs generalized MG. Even though primary outcome was only reached in a single patient at M12, a beneficial effect of RTX on muscle function was seen in half of the patients at M12 and persisted in a third of patients at M18.
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关键词
Myasthenia gravis,anti-AchR,anti-CD20 monoclonal antibodies,anti-acetylcholine receptor antibodies,refractory generalized myasthenia,rituximab
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