Comparison of protective effect of ordinary Cordyceps militaris and selenium-enriched Cordyceps militaris on triptolide-induced acute hepatotoxicity and the potential mechanisms

Lan Wang,Qiong-Hui Huang,Yan-Feng Huang,Jian-Hui Xie,Chang Qu,Jianping Chen,Lin Zheng,Tiegang Yi,Hui-Fang Zeng,Huilin Li

Journal of Functional Foods（2018）

引用 13|浏览9

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摘要

•CS exerted the superior effect on preventing TP-induced acute hepatotoxicity than CM.•CS could activate the Nrf2 signaling pathway and inhibit cellular apoptosis.•CS had higher amounts of cordycepin, Se, selenocystine and polysaccharides than CM.

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关键词

Selenium-enriched Cordyceps militaris,Triptolide,Hepatotoxicity,Antioxidative,Nrf2 pathway,Anti-apoptosis

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