Temperature-modulated cell-separation column using temperature-responsive cationic copolymer hydrogel-modified silica beads.

Kenichi Nagase,Daimu Inanaga,Daiju Ichikawa,Aya Mizutani Akimoto,Yutaka Hattori,Hideko Kanazawa

Colloids and Surfaces B: Biointerfaces（2019）

引用 24|浏览5

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摘要

•A thermoresponsive-cationic beads packed column was developed.•Retention and elution of cells was modulated by changing temperature.•Cell elution behavior was influenced by the anionic properties of cells.•Columns would be useful for cell separation simply by changing temperature.

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关键词

Thermoresponsive polymer,Poly(N-isopropylacrylamide),Cell separation,Temperature-responsive chromatography,Regenerative medicine

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