IL-6 receptor blockade ameliorates diabetic nephropathy via inhibiting inflammasome in mice.

Rui Wu,Xuanchen Liu,Jianyong Yin,Huijuan Wu,Xiulei Cai,Niansong Wang,Youcun Qian,Feng Wang

Metabolism（2018）

引用 74|浏览15

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摘要

The protective effects of an IL-6 receptor blockade against diabetic renal injury may be due to decreased insulin resistance and inhibition of the inflammasome.

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关键词

DN,TCZ,NS,Ins,IgG,MCP-1,8-OHdG,TGF-β1,IL-6,SOCS3,STAT3,NLRP3,IL-1β,IL-18,IL-17A,GTT,ELISA,PAS

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