Affective symptoms and apathy in myotonic dystrophy type 1 a systematic review and meta-analysis.
Journal of Affective Disorders(2019)
摘要
•Myotonic dystrophy type 1 (DM1) is a chronic multisystem hereditary disease.•DM1 patients may show features of depression (18%), anxiety (16%) and/or apathy (55%).•Apathy is a characteristic feature but literature is relatively scarse.•Depression, anxiety may represent reactive adjustments to chronic disease.•Heterogeity between studies is high; most include a limited number of patients.
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关键词
Myotonic dystrophy,Depression,Apathy,Anxiety,Review,Meta-analysis
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