Mining Relationships among Multiple Entities in Biological Networks.
IEEE/ACM Transactions on Computational Biology and Bioinformatics(2020)
摘要
Identifying topological relationships among multiple entities in biological networks is critical towards the understanding of the organizational principles of network functionality. Theoretically, this problem can be solved using minimum Steiner tree (MSTT) algorithms. However, due to large network size, it remains to be computationally challenging, and the predictive value of multi-entity topolog...
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关键词
Steiner trees,Proteins,Diseases,Biological system modeling,Clustering algorithms,Time complexity
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