Detection and Prediction of Bioprosthetic Aortic Valve Degeneration.

Timothy R G Cartlidge,Mhairi K Doris,Stephanie L Sellers,Tania A Pawade,Audrey C White,Renzo Pessotto,Jacek Kwiecinski,Alison Fletcher, Carlos Alcaide,Christophe Lucatelli,Cameron Densem,James H F Rudd,Edwin J R van Beek,Adriana Tavares,Renu Virmani,Daniel Berman,Jonathon A Leipsic,David E Newby,Marc R Dweck

Journal of the American College of Cardiology（2019）

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摘要

F-fluoride PET-CT identifies subclinical bioprosthetic valve degeneration, providing powerful prediction of subsequent valvular dysfunction and highlighting patients at risk of valve failure. This technique holds major promise in the diagnosis of valvular degeneration and the surveillance of patients with bioprosthetic valves. (18F-Fluoride Assessment of Aortic Bioprosthesis Durability and Outcome [18F-FAABULOUS]; NCT02304276).

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关键词

aortic valve replacement,bioprosthetic valve degeneration,calcification,histology,positron emission tomography

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